Solutions of interest include:
Small molecules or peptides that exhibit high levels of TME penetration and selective internalization into pancreatic ductal adenocarcinoma cells
Novel screening system to identify our desired chemical products.

Our must-have requirements are:
In vitro data exhibiting the PDAC cell-selective internalization activity of the compounds or peptides

Our nice-to-have requirements are:
In vitro data is required, but it would be preferred to have animal/in vivo data as well.

What's out of scope:
The compounds or peptides that show specific cell killing activity in PDAC cells without selective internalization activity into the cells are out of scope.

Funding is proposal dependent, with up to $ 150K for 12 month project with potential follow-on funding for 1 year.